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Phosphorylation Motifs Regulating the Stability and Function of Myocyte Enhancer Factor 2A. D.M. Cox, M. Du, M. Marback, E.C.C. Yang, J. Chan, K.W.M. Siu and J.C. McDermott, J. Biol. Chem., 278, 15297-15303 (2003).
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Protein Expression Profiling of Endometrial Malignancies Reveals a New Tumor Marker: Chaperonin 10. E.C.C. Yang, J. Guo, G. Diehl, L. DeSouza, M.J. Rodrigues, A.D. Romaschin, T.J. Colgan and K.W.M. Siu, J. Proteome Res, 3, 636-643 (2004).
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High Level of a-Dioxygenase in Short Styles of Distylous Turnera Species.
D. Khosravi, E.C.C. Yang, K.W.M. Siu and J.S. Shore, Int. J. Plant Sci., 165, 995-1006 (2004).
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Proteomic Analysis of the Proliferative and Secretory Phases of the Human Endometrium: Protein Identification and Differential Protein Expression.
L. DeSouza, G. Diehl, E.C.C. Yang, J. Guo, M.J. Rodrigues, A.D. Romaschin, T.J. Colgan and K.W.M. Siu, Proteomics, 5, 270-281 (2005).
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A Strategy for High-Resolution and Protein Identification in Surface-Enhanced Laser Desorption / Ionization (SELDI) Mass Spectrometry: Calgranulin A and Chaperonin 10 as Protein Markers for Endometrial Carcinoma.
J. Guo, E.C.C. Yang, L. DeSouza, G. Diehl, M.J. Rodrigues, A.D. Romaschin, T.J. Colgan and K.W.M. Siu, Proteomics, 5, 1953-1966 (2005).
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Search for Cancer Markers from Endometrial Tissues using Differentially Labeled Tags iTRAQ and cICAT with Multidimensional Liquid Chromatography and Tandem Mass Spectrometry. L. DeSouza, G. Diehl, M.J. Rodrigues, J. Guo, A.D. Romaschin, T.J. Colgan and K.W.M. Siu, J. Proteome Res., 4, 377-386 (2005).
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Direct Analysis of Laser Capture Microdissected Endometrial Carcinoma and Epithelium by MALDI Mass Spectrometry. J. Guo, T.J. Colgan, L. DeSouza, M.J. Rodrigues, A.D. Romaschin and K.W.M. Siu, Rapid Commun. Mass Spectrom., 19, 2762-2766 (2005).
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Genomic and Proteomic Evidence for a Second Family of Dense Core Granule Cargo Proteins in Tetrahymena thermophila. G.R. Bowman, D.G.S. Smith, K.W.M. Siu, R.E. Pearlman and A.P. Turkewitz, J. Eukaryot. Microbiol., 52, 291-297 (2005).
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A Proteomics Approach to the Study of Distyly in Turnera Species.
D. Khosravi, K.W.M. Siu and J.S. Shore, In J.A. Teixeira da Silva, Ed. “Floriculture, Ornamental and Plant Biotechnology: Advances and Topical Issues” Volume 1, Global Science Books, U.K., pp. 51-60 (2006).
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Characterization of the Human Proliferative Cell Nuclear Antigen Physico-Chemical Properties: Aspects of Double Trimer Stability. S.N. Naryzhny, L.V. DeSouza, K.W.M. Siu and H. Lee, Biochem. Cell Biol., 84, 669-676 (2006).
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The Tetrahymena thermophila Phagosome Proteome. M.E. Jacobs, L.V. DeSouza, H. Samaranayake, R.E. Pearlman, K.W.M. Siu and L.A. Klobutcher, Eukaryot. Cell, 5, 1990-2000 (2006).
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Comparison of Methods to Examine the Endogenous Peptides of Fetal Calf Serum.
D. Williams, P. Zhu, P. Bowden, C. Stacey, M. McDonell, P. Kowalski, J.M. Kowalski, K. Evans, E.P. Diamandis, K.W.M. Siu and J. Marshall, Clin. Proteomics, 2, 67-90 (2006).
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Endometrial Carcinoma Biomarker Discovery and Verification Using Differentially Tagged Clinical Samples with Multidimensional Liquid Chromatography and Tandem Mass Spectrometry. L.V. DeSouza, J. Grigull, S. Ghanny, V. Dubè, A.D. Romaschin, T.J. Colgan and K.W.M. Siu, Mol. Cell. Proteomics, 6, 1170-1182 (2007).
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Identification of Candidate Biomarker Proteins Released by Human Endometrial and Cervical Cancer Cells Using Two-Dimensional Liquid Chromatography / Tandem Mass Spectrometry. H. Li, L.V. DeSouza, S. Ghanny, W. Li, A.D. Romaschin, T.J. Colgan and K.W.M. Siu, J. Proteome Res., 6, 2615-2622 (2007).
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Verification of Endometrial Tissue Biomarkers Previously Discovered Using Mass-Tagging and Multidimensional Liquid Chromatography / Tandem Mass Spectrometry by means of Immunohistochemistry in a Tissue Microarray Format.
V. Dubè, J. Grigull, L.V. DeSouza, S. Ghanny, T.J. Colgan, A.D. Romaschin and K.W.M. Siu, J. Proteome Res. 6, 2648-2655 (2007).
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Exploring the Mitochondrial Proteome of the Ciliate Protozoon, Tetrahymena thermophila: Direct Analysis by Tandem Mass Spectrometry. D.G.S. Smith, R.M.R. Gawryluk, D.F. Spencer, R.E. Pearlman, K.W.M. Siu, and M.W. Gray, J. Mol. Biol., 374, 837-863 (2007).
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Diversity of Pencillin-Binding Proteins Resistance Factor FmtA of Staphylococcus Aureus. X. Fan, Y, Liu, D. Smith, L. Konermann, K.W.M. Siu and D. Golemi-Kotra, J. Biol. Chem., 282, 35143-35152 (2007).
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Proteomics: Current and Future Implications in Neurooncology. J. Micallef, A. Gajadjar, J. Wiley, L.V. DeSouza, K.W.M. Siu and A. Guha, Neurosurgery, 62,539—555 (2008).
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Discovery and Verification of Head-and-Neck Cancer Biomarkers by Differential Protein Expression Analysis using iTRAQ-labeling and Multidimensional Liquid Chromatography and Tandem Mass Spectrometry.
R. Ralhan, L.V. DeSouza, A. Matta, S.C. Tripathi, S. Ghanny, S. Datta Gupta, S. Bahadur and K.W.M. Siu, Mol. Cell. Proteomics, 7, 1162-1173 (2008).
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Prognostic Significance of Head-and-Neck Cancer Biomarkers Previously Discovered and Identified Using iTRAQ-Labeling and Multidimensional Liquid Chromatography — Tandem Mass Spectrometry.
A. Matta, L.V. DeSouza, S. Bahadur, S.D. Gupta, R. Ralhan and K.W.M. Siu, J. Proteome Res., 7, 2078-2087 (2008).
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Multiple Reaction Monitoring of mTRAQ Labeled Peptides Enables Absolute Quantification of Endogenous Levels of a Potential Cancer Marker in Cancerous and Normal Endometrial Tissues.
L.V. DeSouza, A.M. Taylor, W. Li, M.S. Minkoff, A.D. Romaschin, T.C. Colgan and K.W.M. Siu, J. Proteome Res., 7, 3525-3534 (2008).
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Study of an RNA Helicase Implicates Small RNA-Noncoding RNA Interactions in Programmed DNA Elimination in Tetrahymena.
L. Aronica, J. Bednenko, T. Noto, L.V. DeSouza, K.W.M. Siu, J. Loidl, R.E. Pearlman, M.A. Gorovsky and K. Mochizuki, Genes & Dev., 22, 2228-2241 (2008).
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Differential Protein Expressions in Renal Cell Carcinoma: New Biomarker Discovery by Mass Spectrometry.
K.W.M. Siu, L.V. DeSouza, A. Scorilas, A.D. Romaschin, R.J. Honey, R. Stewart, K. Pace, Y. Youssef, T.F.F. Chow and G.M. Yousef, J. Proteome Res., 8, 3797-3807 (2009).
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iTRAQ-Multidimensional Liquid Chromatography and Tandem Mass Spectrometry based Identification of Potential Biomarkers of Oral Epithelial Dysplasia and Novel Networks between Inflammation and Premalignancy.
R. Ralhan, L.V. DeSouza, A. Matta, S.C. Tripathi, S. Ghanny, S.D. Gupta, A. Thakar, S.S. Chauhan and K.W.M. Siu, J. Proteome Res., 8, 300-309 (2009).
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Exploring the Pathogenesis of Renal Cell Carcinoma: Pathway and Bioinformatics Analysis of Dysregulated Genes and Proteins.
A.D. Romaschin, Y. Youssef, F.T. Chow, K.W.M. Siu, L.V. DeSouza, R.J. Honey, K.T. Pace, R. Steward and G.M. Yousef, Biol. Chem., accepted October 1, 2008.
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Absolute Quantification of Potential Cancer Markers in Clinical Tissue Homogenates using Multiple Reaction Monitoring on a Hybrid Triple Quadrupole / Linear Ion Trap Tandem Mass Spectrometer.
L.V. DeSouza, A.D. Romaschin, T.J. Colgan and K.W.M. Siu, Anal. Chem., 81, 3462-3470 (2009).
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Heterogeneous Ribonucleoprotein K (hnRNP K) is a Marker of Oral Leukoplakia and Correlates with Poor Prognosis of Squamous Cell Carcinoma.
A. Matta, S.C. Tripathi, L.V. DeSouza, J. Grigull, J. Kaur, S.S. Chauhan, A. Srivastava, A. Thakar, N.K. Shukla, R. Duggal, S. DattaGupta, R. Ralhan and K.W.M. Siu. Int. J. Cancer., 125, 1398-1406 (2009).
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Loss of Collapsin Response Mediator Protein 1 (CRMP1) as Detected by iTRAQ Analysis Promotes Invasion of Human Gliomas Expressing Mutant EGFRvIII.
J. Mukherjee, L.V. DeSouza, J. Micaleff, Z. Karim, S. Croul, K.W.M. Siu and A. Guha, Cancer Res., 69, 8545-8554 (2009) published on the Web, November 10, 2009.
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Mass Spectrometry-Based Clinical Proteomics: Opportunities and Challenges in Head-and-Neck Cancer Biomarker and Drug Target Discovery.
A. Matta, R. Ranju, L.V. DeSouza and K.W.M. Siu, Mass Spectrom. Rev., accepted June 29, 2009.
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Two GW Repeat Proteins Interact with the Tetrahymena Argonaute and Promote Genome Rearrangement.
J. Bednenko, T. Noto, L.V. DeSouza, K.W.M. Siu, R.E. Pearlman, K. Mochizuki and M.A. Gorovsky, Mol. Cell. Biol., 29, 5020-5030 (2009).
- The Tetrahymena Argonaute-Binding Protein Giw1p Directs a Mature Argonaute-siRNA to the Nucleus.
T. Noto, H.M. Kurth, K. Kataoka, L. Aronica, L.V. DeSouza, K.W.M. Siu, R.E. Pearlman, M.A. Gorovsky and K. Mochizuki, Cell, accepted , December 2009.
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