BIOL 5037 1.5

Advanced Genetics

 Course Description:

This core course will address recent advances in Drosophila, C. elegans  and plant genetics.  Techniques such as genetic dissection, mutagenesis, genetic screens, methods for manipulating genes, chromosomal analysis, transposon and enhancer tagging, positional cloning and QTL analyses will be included in the lecture topics.

The course will be offered as 3 hr lectures per week for a 6 week period.

 Prerequisite: Undergraduate Introductory Genetics Course.

Course Director:

Dr. A. Hilliker

Office:  002 Farquharson

Telephone: 416-736-2100 ext. 77876

e-mail: hilliker@yorku.ca

Evaluation:

1 Seminar (one hour in length) – oral presentation derived from the primary literature chosen by the student in consultation with the course director.

- worth 40%

1 Research Grant Proposal (15 pages long) on a topic unrelated to the student’s thesis work.  The research grant will include a literature survey, a research proposal of at least eight experiments including a rationale for the experiments, the experimental design, the methods for data collection and analyses and interpretations of the experimental outcomes.  The research grant will also include a summary of short and long term research goals.

• worth 50%

10% Participation

Bibliography:

Journals:

Genetics

Science

Nature

Nature Genetics

Genes and Development

Heredity

Plant Cell

Genome