BIOL 5130 3.0 CR=3.0
CARDIOVASCULAR SYSTEMS IN HEALTH & EXERCISE
Cross-Listed with KAHS 5300 3.0 – host program
This core course is an in‑depth study of the cardiovascular system during exercise and disease, including an examination of current research. It is designed to further an understanding of selected, current and advanced topics in cardiovascular exercise physiology through:1) lectures, 2) laboratories, and 3) the reading and discussion of current research literature. The topics covered are devoted to both the central (heart) and peripheral (blood flow) circulation, with an emphasis on health, disease and adaptation. The course emphasizes the cellular and molecular basis of cardiovascular physiology in these areas.
Prerequisite: York undergraduate course Arts/Science Kinesiology and Health Science 4010 3.0: Physiology of Exercise or equivalent.
Degree credit exclusion: Kinesiology and Health Science 4450 3.0
Dr. O. Birot
Lecture Exam: 35%
Lab Exam: 35%
Paper presentation: 20%
These references are available in the Steacie Science Library.
1. Berne, R.M. and M.N. Levy. Cardiovascular Physiology, 7ed. St. Louis: Mosby, 1997. (QP 102 B47 1992) (BL)
2. Mohrman, D.E. and L.J. Heller. Cardiovascular Physiology, 4ed. New York: McGraw-Hill, 1997. (QP 102 M621991)(MH)
3. Rowell, L.B. Human Cardiovascular Control. New York: Oxford, 1993. (QP 109 R68 1993)(LBR)
4. Levick, J.R. An Introduction to Cardiovascular Physiology. Oxford: Butterworth-Heineman, 1995 (JRL).
5. Smith, J.J. and J.P. Kampine. Circulatory Physiology: the Essentials, 3ed. Baltimore: Williams and Wilkins, 1990. (QP 102 S64 1990) (SK)
6. Honig, C.R. Modern Cardiovascular Physiology, 2ed. Boston: Little, Brown, 1988.
(QP 102 H66 1988)(CRH)
7. Rowell, L.B. Human Circulation: Regulation during Physical Stress. New York: Oxford Press, 1986. (QP 102 R69 1986)(LBR2)
8. Roberts, R. Molecular Basis of Cardiology. Boston: Blackwell Scientific, 1993. (QP 669.9M65 1993)
9. Ruegg, J.C. Calcium in Muscle Contraction, 2ed. Berlin: Springer-Verlag, 1992.(JCR)
10. Fletcher, G.F. et al. Exercise Standards. Circulation 91:580-615, 1995. (RC 681 A1 C54)
11. Opie, L.H. The Heart: Physiology and Metabolism. New York: Raven, 1991. (QP 111.4 O64 1991)(Opie)
12. Katz, A.M. Physiology of the Heart, 2ed. New York: Raven, 1992. (QP 111.4 K38 1992)(Katz)
13. Braunwald, E., J. Ross and E.H. Sonnenblick. Mechanisms of Contraction of the Normal and Failing Heart. New York: Little, Brown, 1968.
14. Langer, G.A. and A.J. Brady. The Mammalian Myocardium. New York: Wiley, 1974.
15. Issues of Medicine and Science in Sports and Exercise May 1997 and March 1998 have topics on VO2 max, blood flow etc...
16. Nishio, M.L., Ornatsky, O.I., Craig, E.E., and Hood, D.A. (1995). Mitochondrial biogenesis during pressure overload induced cardiac hypertrophy in adult rats. Can. J. Physiol. Pharmacol. 73: 630-637.
17. Parker, T.G., Marks, A., and Tsoporis, J.N. (1998). Induction of S100β in myocardium: an intrinsic inhibitor of cardiac hypertrophy. Can. J.Appl. Physiol. 23:377-389, 1998.
18. Sadoshima, J., and Izumo, S. (1997). The cellular and molecular response of cardiac myocytes to mechanical stress. Annu. Rev. Physiol. 59: 551-571.