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Derek J. Wilson PhD (Western Ontario), Assistant Professor Office: 318 CB Telephone: 416 416 736 2100 ext. 20786 E-mail: dkwilson@yorku.ca Web: www.yorku.ca/dkwilson Research Interests: Protein Dynamics, Microfluidics, Time-resolved Mass Spectrometry, Biophysical NMR

Affiliations: Centre for Research in Biomolecular Interactions

Research is focused on the relationship between the conformational motions of proteins in solution (their dynamics) and their biological activity. The primary tool is Time- Resolved Electrospray Mass Spectrometry, a method that allows a wide range of active biochemical processes to be monitored on short (millisecond-to-second) timescales. This technique is combined with a number of other techniques, including biophysical NMR and H/D exchange to obtain a highly detailed, dynamic picture of protein function. There is also a significant technology development component to the work.