| |
|
|
David Hood
Professor and Canada Research Chair
Director, Muscle Health Research Centre
Research interests:
Research in skeletal muscle and heart biochemistry and molecular biology; mitochondrial adaptations in muscle subject to exercise, including mechanisms of mitochondrial protein import, nuclear gene expression and apoptosis; muscle adaptations to thyroid hormone.
Contact:
E-mail | Website | (416) 736-2100 ext. 66640 | 302 Farquharson Building, 110 Campus Walk. |
|
|
Olasunkanmi Adegoke
Research interests:
Protein metabolism is health and disease. Emphasis is on the ubiquitin proteasome degradation system in skeletal muscle, and its activity and expression during nutritional and hormonal states of muscle wasting.
Contact:
E-mail | (416) 736-2100 ext. 20887 | 362
Norman Bethune College, 170 Campus Walk. |
|
 |
Angelo Belcastro
Research interests:
Muscle injury and damage in health and disease. With particular reference to calcium-induced protein degradation processes (calpain-calpastatin targeted substrates) in skeletal muscle during periods of increased/decreased contractile activity.
Contact:
E-mail | (416) 736-2100 ext.21088 | 333B
Norman Bethune College, 170 Campus Walk. |
|
|
Olivier Birot
Research interests:
Research in muscle angio-adaptation in response to physiological (exercise, physical inactivity, altitude) and pathological (diabetes, peripheral arterial disease) conditions; Molecular mechanisms involved either in regression or growth (angiogenesis) of capillaries in skeletal and cardiac muscles.
Contact:
E-mail | Website | (416) 736-2100 ext. 44043 | 353
Norman Bethune College, 170 Campus Walk. |
|
|
Enzo Cafarelli (Professor Emeritus)
Research interests:
The neural control of skeletal muscle. Emphasis is on the strategies employed by the CNS to offset changes in the contractile properties of muscle that become altered by different patterns of usage such as fatigue and training.
Contact:
E-mail |
|
|
Rolando Ceddia
Research interests:
The physiological and molecular mechanisms that regulate glucose and fatty acid uptake and metabolism in skeletal muscle and adipose tissue. The major focus is on dysfunctional metabolic alterations associated with obesity and Type 2 Diabetes.
Contact:
E-mail | (416) 736-2100 ext. 77204 | 225A
Lumbers Building, 115 Ottawa Road. |
|
|
Imogen Coe (Adjunct Member)
Research interests:
Research is focused on a family of membrane proteins that are involved in the transport of nucleosides such as adenosine. Not only are these transporters important in the general homeostasis of all cells, they are also of critical clinical importance in the treatment of cancer and systemic viral infection.
Contact:
E-mail |
|
|
Michael Connor
Research interests:
The role of the cell cycle in muscle development and breast cancer; 1) investigating the signalling mechanisms determining how dividing muscle cells becomes fully differentiated skeletal muscle; 2) characterization of novel proteins elevated in breast cancer.
Contact:
E-mail | (416) 736-2100 ext. 77206 | 224
Lumbers Building, 115 Ottawa Road. |
|
|
William Gage
Research interests:
Research in neuromuscular control of posture, balance, and gait; influence of pathology, such as osteoarthritis, ankylosing spondylitis, and stroke on muscle activation characteristics as related to joint stability and control of movement.
Contact:
E-mail | Website | (416) 736-2100 ext. 33027 | 2022 Sherman Health Science Research Centre. |
|
|
Tara Haas
Research interests:
Blood vessel growth (angiogenesis) in skeletal muscle; biochemical, cellular and molecular biological approaches are used to study the stimuli and signalling pathways that cause endothelial cells to initiate angiogenesis as a result of exercise or disease.
Contact:
E-mail | (416) 736-2100 ext. 77313 | 341 Farquharson Building, 110 Campus Walk. |
|
|
Mazen Hamadeh
Research interests:
Animal studies: Effect of caloric restriction, functional foods and antioxidants on the oxidative status, clinical onset, disease progression and life span in the G93A mouse, an animal model of amyotrophic lateral sclerosis (Lou Gehrig’s disease). Human studies: Protein metabolism, glucose turnover and substrate oxidation in humans during endurance exercise re: gender differences, diabetes and aging.
Contact:
E-mail | Website | (416) 736-2100 ext. 33552 | 365
Norman Bethune College, 170 Campus Walk. |
|
|
Tom Hawke (Adjunct Member)
Research interests:
Molecular regulation of skeletal muscle regeneration; Regulation of muscle stem cells in the repair of skeletal muscle following exercise and disease-induced myotrauma. What intrinsic factors are responsible for regulating stem cell quiescence, activation, proliferation and differentiation?
Contact:
E-mail |
|
|
Ira Jacobs (Adjunct Member)
Research interests:
Muscle metabolism during exercise; Exercise pharmacology and relationship to performance in environmentally stressful conditions.
Contact:
E-mail |
|
 |
Jennifer Kuk
Research interests:
Characterizing obesity and related health risks (cardiovascular disease and type 2 diabetes) and examining the influence of physical activity using both exercise interventions and epidemiological approaches.
Contact:
E-mail | (416) 736-2100 ext.
20080 | 2002 Sherman Health Science Research Centre. |
|
|
John McDermott
Research interests:
Research interests concern the basic regulatory mechanisms involved in muscle cellular differentiation. This work is primarily undertaken using muscle cells as a model system and is aimed at understanding the role of transcription factors in orchestrating muscle-specific differentiation.
Contact:
E-mail | (416) 736-2100 ext. 30389 | 327
Farquharson Building, 110 Campus Walk. |
 |
Christopher Perry
Research interests:
Regulation of cellular energy and redox homeostasis primarily in skeletal muscle. Examination of metabolic control (glucose/fatty acid uptake and catabolism) through redox biology in response to specific dietary and exercise interventions integrating mitochondrial, cytosolic and nuclear intercommunication.
Contact:
Email | (416) 736-2100 ext.
33232
|
324 Norman Bethune College, 170 Campus Walk.
|
|
|
Michael Riddell
Research interests:
The effect of exercise, stress and diabetes on the hypothalamo-pituitary-adrenal (HPA) axis. Substrate utilization and metabolism during exercise in individuals with Type 1 and Type 2 diabetes mellitus.
Contact:
E-mail | Website | (416) 736-2100 ext. 40493 | 347
Norman Bethune College, 170 Campus Walk.
Physical Activity and Diabetes (PAD) Initiative |
|
|
Anthony Scimè
Research Interests:
Physiological and molecular mechanisms that regulate skeletal muscle and adipose tissue differentiation. Molecular networks that regulate adipocyte and muscle stem cell quiescence, activation, proliferation and differentiation. The ultimate aim is to understand mechanisms of muscle tissue regeneration and adipocyte cell type switching.
Contact:
E-mail | (416) 736-2100 ext. 33559 | 327C
Norman Bethune College, 170 Campus Walk. |
|
|
Robert Tsushima
Research interests:
Research is focused on cardiac muscle physiology and disease. There are two specific research projects focusing on cell physiology and heart disease. First, investigations are ongoing on the role of SNARE proteins in the heart, and how they modulate voltage-gated ion channels. Second, cell signalling pathways involved in mediating myocardial ischemic preconditioning using genetically-modified mouse models are examined.
Contact:
E-mail | (416) 736-2100 ext. 20996 | 344
Farquharson Building, 110 Campus Walk. |
|
