CLINICAL NEUROPSYCHOLOGY ROUNDS 2012-2013
Oct 1, 2012, 1:15pm-2:30pm
Mario Masellis, M.Sc., M.D.
Division of Neurology and Brain Sciences Program
Sunnybrook Research Institute and Health Sciences Centre
“The Lewy body disease spectrum: clinical, neuropsychological and neuroimaging perspectives.”
Dementia with Lewy bodies (DLB), Parkinson's disease-mild cognitive impairment (PD-MCI), and Parkinson's disease dementia (PDD) are neurodegenerative disorders characterized by the pathological hallmark of intraneuronal Lewy bodies and neurites, comprised of insoluble α-synuclein. Collectively, they are known as Lewy body disease (LBD). Although duration of motor symptoms at the time of dementia onset helps to distinguish across the spectrum of LBD, in many circumstances this information does not suffice for diagnosis and other historical/examination features and investigations may be useful. Although cholinesterase inhibitors are the mainstay of therapy for dementia associated with LBD, intolerance is a major issue in a significant subset of patients. 'Non-dementia' symptoms may also be contributing to the overall cognitive decline and these should be addressed.
Faculty and students welcome
Refreshments will be served
Mark your calendars for York’s Clinical Neuropsychology Rounds
First Monday October-April
|Posted by:||Dr. Walter Heinrichs|