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Triumph of Discovery: York Alumni Shine with Prestigious 2024 Polanyi Prizes

In the heart of Ontario’s vibrant academic landscape, two York University alumni have etched their names into the archives of research excellence, earning the prestigious John Charles Polanyi Prizes for 2024. Dr. Nikolai M. Cook and Dr. Hossein Davarinejad, both trailblazers in their respective fields, have been recognized for their groundbreaking contributions to physiology/medicine and economic sciences. Their achievements not only highlight their individual brilliance but also shine a spotlight on the York University community, which celebrates their success with immense pride.

Nikolai M. Cook (MA ’14)—Economic Science

Dr. Cook completed his MA in Economics at York, and obtained his PhD in Economics from the University of Ottawa. As an assistant professor at Wilfrid Laurier University, he is redefining what it means to do meaningful economic research—by making it both more transparent and more urgent.

Through innovative tools that expose publication bias and p-hacking, and by championing pre-analysis plans, he’s laying the groundwork for a more honest, accountable, and reliable field of economics. But his impact doesn’t stop there. Cook also explores how the environment—specifically climate change and air pollution—is shaping economic realities.

His research shows that rising temperatures and even low levels of pollution impair productivity and cognitive performance. His findings point to surprisingly simple interventions, like better indoor climate control and changing building layouts, that can help protect workers and communities.

In his latest work, he reveals how hotter days in North America are already linked to increases in gun violence, using innovative data from real-time gunshot detection systems. As he looks ahead, Cook aims to expand his focus to developing countries, where climate vulnerability is greatest.

photo of Dr. Nikolai M. Cook

Photo of Dr. Nikolai M. Cook

photo of Dr. Hossein Davarinejad

Photo of Dr. Hossein Davarinejad

Hossein Davarinejad (MSc ’15)—Physiology/Medicine

Dr. Davarinejad earned his MSc in Molecular Biology from York, and obtained his PhD in Biochemistry from the University of Ottawa. As a postdoctoral fellow at the University of Ottawa, he is on a mission to decode this complexity. His groundbreaking research focuses on histones, the DNA-wrapping proteins that help control which genes turn on or off.

By exploring how chemical changes to histones—especially variants of Histone H3—regulate crucial cellular processes like DNA repair and nuclear structure, Davarinejad aims to illuminate the molecular dance that keeps our genes in check. Using advanced tools like cryo-electron microscopy and X-ray crystallography, he is uncovering how key enzymes like ATXR5/6 orchestrate these changes, offering a model that could unlock similar mechanisms in humans.

This work doesn’t just deepen our understanding of cellular function—it paves the way for future therapies targeting the very root of genetic misfires. By revealing how cells remember, repair, and regulate, this research holds promise for rewriting the future of medicine, one atom at a time.

Established in honor of John Charles Polanyi, the University of Toronto’s Nobel Prize-winning chemist, the Polanyi Prizes are awarded annually by the Ontario government through the Council of Ontario Universities. Each recipient, an early-career researcher at an Ontario university, receives $20,000 in recognition of their exceptional contributions across fields like chemistry, physics, literature, economic sciences, and physiology/medicine. The 2024 awards, announced on December 10, 2024, celebrate researchers whose work drives innovation and addresses pressing societal challenges, from healthcare advancements to economic resilience.

For York University, the success of Cook and Davarinejad is a moment of collective pride. “Ontario’s researchers represent some of the best and brightest minds in the world,” said the Honourable Jill Dunlop, Minister of Colleges and Universities, in a statement. “Recipients of the John C. Polanyi Prizes are tackling some of the most challenging issues facing our society, and, in turn, continue to position Ontario as an international leader in research.” The York community echoes this sentiment, celebrating the role its graduate programs played in shaping these scholars’ paths.

Cook’s and Davarinejad’s achievements highlight the strength of York’s commitment to fostering innovative thinkers. Their time at York equipped them with the tools to question, explore, and innovate, laying the foundation for their award-winning research. As alumni, they carry forward York’s legacy of excellence, demonstrating how curiosity and dedication can lead to solutions that benefit society at large.

The 2024 Polanyi Prizes serve as a reminder of the power of research to transform lives and communities. For Dr. Nikolai M. Cook and Dr. Hossein Davarinejad, this recognition is not just a milestone but a call to continue their pursuit of knowledge. The York University community beams with pride, knowing that its alumni are leading the charge in creating a brighter, more innovative future for Ontario and beyond.

Sources: Ontario Newsroom, December 10, 2024; Council of Ontario Universities, 2024.
Ontario Newsroom release | Ontario’s Universities profile