Midbrain Reticular Formation
Using
a
combination
if single unit recording, microstimulation, and injection of muscimol,
we
have shown that the Intersitial Nucleus of Cajal (INC) contains 'neural
integrators'
that control the three-dimensional orientation of both the eye and the
head.
We have also shown that the INC and adjacent riMLF burst neurons
utilize
a coordinate
system
similar to the semicircular canals, but aligned with the behavioral
constraints
(Listing's law, Fick strategy) observed in eye and head movements. Now
we
are looking at how these areas separately control the eye and head, and
how
they control neck muscles.
FARSHADMANESH F, KLIER EM, CHANG P, WANG H, CRAWFORD JD (2007)
Three dimensional eye-head coordination after unilateral inactivation of the interstital nucleus of Cajal (INC) in the primate.
Journal of Neurophysiology (Published On-line)
KLIER EM, WANG H, CRAWFORD JD (2007)
The Interstitial Nucleus of Cajal Encodes Three-Dimensional Head Orientations in Fick-like Coordinates.
Journal of Neurophysiology 97(1): 604-17
CRAWFORD JD, TWEED DB, VILIS T (2003)
Static ocular counterroll is implemented through the 3-D neural integrator
Journal of Neurophysiology 90: 2777-2784
KLIER EM, WANG H,
CONSTANTIN A, CRAWFORD JD
(2002)
Midbrain control of
three-dimensional head orientation
Science
295: 1314-1316
CRAWFORD JD (1994)
The oculomotor neural integrator uses a behavior-related coordinate
system
The Journal of Neuroscience
14(11): 6911-6923
CRAWFORD JD, VILIS T
(1993)
Modularity and parallel processing in the oculomotor integrator
Experimental
Brain Research 96(3): 443-456
CRAWFORD JD, VILIS T
(1992)
Symmetry of oculomotor
burst neurons coordinates about Listing's plane
Journal
of Neurophysiology 68(2): 432-448
CRAWFORD JD, CADERA W, VILIS T (1991)
Generation of torsional and vertical eye position signals by the interstitial nucleus of Cajal
Science 252: 1551-1553
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