Worried about vaccine side effects? Check out Dr. Ali Abdul-Sater's comments on Y-file

Paper of the month (May 2021) from Dr. Olasunkanme (Ola) Adegoke's research group

Mann, G., & Adegoke, O. (2021). Effects of ketoisocaproic acid and inflammation on glucose transport in muscle cells. Physiological reports, 9(1), e14673. https://doi.org/10.14814/phy2.14673 Significance of the research: Type 2 diabetes and cardiovascular diseases affect millions of people world-wide, with the attending implications for morbidity and mortality. An underlying cause of these diseases is insulin resistance, especially skeletal […]

Y-File News: Muscle Health Awareness Day features eight speakers for 12th annual event

Join Will Gage, associate vice-president, teaching & learning, and Joy Kirchner, dean of libraries, on May 6 from 1 to 4 p.m. for a non-traditional conference, Open Space for Open Education, to help shape the University’s further engagement with open educational practices and OER.

Paper of the month (April 2021) from Dr. Ronald Ceddia's research group

Da Eira, D., Jani, S., Sung, H., Sweeney, G., & Ceddia, R. B. (2020). Effects of the adiponectin mimetic compound ALY688 on glucose and fat metabolism in visceral and subcutaneous rat adipocytes. Adipocyte, 9(1), 550–562. https://doi.org/10.1080/21623945.2020.1817230   Significance of the research: Adiponectin is an adipose-derived hormone that is significantly reduced in the blood of obese and type 2 diabetic […]

Drs. Christopher Perry and David Hood interviewed in Nature Outlook for a feature on "Unlocking the mysteries of mitochondria: The Key to Endurance".

Sports Science Outlook [PDF]

Paper of the month (March 2021) from Dr. Heather Edgell's research group

Nardone M, Guzman J, Harvey PJ, Floras JS, Edgell H. Effect of a neck compression collar on cardiorespiratory and cerebrovascular function in postural orthostatic tachycardia syndrome (POTS). J Appl Physiol (1985). 2020;128(4):907‐913. doi:10.1152/japplphysiol.00040.2020 Significance of the research: Postural orthostatic tachycardia syndrome (POTS) is marked by an excessive increase of heart rate in the upright posture […]

Paper of the month (February 2021) from Dr. Peter Backx's research group

Zhao Y, Rafatian N, Backx PH, et al. Engineering microenvironment for human cardiac tissue assembly in heart-on-a-chip platform. Matrix Biol. 2020;85-86:189-204. doi:10.1016/j.matbio.2019.04.001   Significance of the research The generation of heart tissues from pluripotent stem cells is hampered by the lack of cellular maturation as well as problems with cellular composition. In addition to cardiomyocytes, […]

Professor Michael Riddell will be a presenter at Celebrating the 100th Anniversary of the Discovery of Insulin: Diabetes Research and Innovation in the Making

Insulin, the most important hormone for the control of metabolism in the body, was discovered 100 years ago by Fredrick Banting, Charles Best and James Collip under the directorship of Professor John Macleod at the University of Toronto. The discovery of insulin earned Banting and Macleod the Nobel Prize in 1923, and people around the […]

New paper by PhD candidate Jonathan Memme and Dr. David Hood illustrates the benefits of exercise as "Mitochondrial Medicine" for muscle with age and disease.