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Derek Wilson

Derek Wilson

Picture of Derek Wilson
Derek Wilson
Full Professor, Research Stream


York Research Chair (Tier 2)

Eligible to Supervise

Biology Graduate Program, Physics and Astronomy Graduate Program


Wilson Lab


Office Location 331C LSB
Phone Number (416)736-2100 x 20786 (Voicemail)

Research Interests

Protein Dynamics, Microfluidics, Time-resolved Mass Spectrometry, Biophysical NMR

Research is focused on the relationship between the conformational motions of proteins in solution (their dynamics) and their biological activity. The primary tool is Time- Resolved Electrospray Mass Spectrometry, a method that allows a wide range of active biochemical processes to be monitored on short (millisecond-to-second) timescales. This technique is combined with a number of other techniques, including biophysical NMR and H/D exchange to obtain a highly detailed, dynamic picture of protein function. There is also a significant technology development component to the work.


Analytical Chemistry, Biological Chemistry

UN Goals

Good Health and Well-being