Skip to main content Skip to local navigation
Home » Research » Funding Opportunities » Canadian Cancer Society: Breakthrough Team Grants: Transforming Low Survival Cancers

Canadian Cancer Society: Breakthrough Team Grants: Transforming Low Survival Cancers

Opportunity NameTransforming Low Survival Cancers Breakthrough Team Grant
AgencyCanadian Cancer Society and Canadian Institutes of Health Research - Institute of Cancer Research
ValueUp to $1,500,000
Indirect CostsIneligible
DurationUp to 5 years
Expression of Interest (EOI) due to faculty and SIRI06-22-2022
EOI webinar 06-28-2022, 12:00 to 4:00PM
Registration deadline 07-26-2022
Full draft of application due to SIRI for SPORT review 09-20-2022
Application and fully signed ORS checklist due to FSc RO at for mandatory review10-12-2022
Final application and fully signed ORS checklist due to SIRI for mandatory review10-18-2022
Application due at agency 10-19-2022

The intent of the CCS Breakthrough Team Grants: Transforming Low Survival Cancers is to bring together the sharpest minds and research talent from across Canada and beyond. By combining scientific, clinical, and patient expertise, in a collaborative, interdisciplinary environment and integrating the power of new technologies and interventions, we hope to find new ways to prevent the onset of these six cancers (pancreas, esophagus, brain, lung, liver, stomach), improve survival through early detection when the disease is at its most treatable, including the early detection of recurrence and metastatic spread, and develop more precise and effective treatments with fewer harmful side effects. 

The goals of this funding opportunity are to:  

  • Focus national and international (as a Collaborator or Co-applicant) cancer expertise on these six low survival cancers to drive a paradigm shift in prevention, detection, treatment and care.
  • Ensure the relevance of the research conducted by engaging clinicians and other healthcare professionals, as well as patients and caregivers with lived experience of the cancers under study, in the research project from the outset, including in the design of applications.
  • Build capacity to sustain future research through the recruitment of clinicians and clinician scientists, as well as the inclusion and training of early career investigators and trainees to build scientifically strong teams and continue the momentum into the future.
  • Leverage, or build, the necessary national and international resources, platforms, pipelines and infrastructure required to answer the most critical questions related to these cancers.
  • Broaden the traditional research focus by harnessing expertise, resources, platforms and technologies from both across and outside the cancer field to create novel and innovative solutions.
  • Explore opportunities to adapt successful approaches used in other cancer types or other health conditions to the cancers under study here. 
  • In those cancers with existing capacity and resources, generate progress leading to clinical trials/first in-human studies before the end of the five-year granting period.
  • Include considerations not just of extending life but also improving the quality of life for individuals living with these challenging cancers, including symptom control, psychosocial and supportive care, as well as palliative and end-of life care.
  • Fully engage the appropriate stakeholders needed to move new findings into action and application to ensure that new advances are made available for everyone in Canada.

  • An applicant must hold a firm academic position (as a primary appointment) which allows the individual to engage in independent research activities for the duration of the project and includes the ability to supervise trainees and publish research results.
  • A researcher designated as the Principal Investigator must be based in, or formally affiliated with, an eligible Canadian Host Institution such as a university, research institute or health care agency. 
  • The person named as the PI remains the PI on a grant for the duration of the grant unless given express permission by the Canadian Cancer Society.

How to Apply

All researchers should notify both their Faculty and Diana Frasca ( as soon as possible about their intention to apply. Doing so will streamline the process of ensuring that researchers receive adequate support in application preparation. 

York University researchers are reminded that all applications for external research funding, including Letters of Intent, must be reviewed and approved by the Office of Research Services before they are submitted to the granting agency.  For internal approval, the application must be accompanied by a completed ORS Checklist, which requires the Dean’s signature.  Please send the complete application, with the finalized budget and a completed ORS checklist to, five days prior to agency deadline.

ORS is accepting electronic applications – the process is outlined here.

For specific questions, please contact your FSc Research Officer

Stefanie Bernaudo
Research Officer
(Biology, Physics & Astronomy, Science, Technology & Society)

Phoebe Tsz-Wai Chan
Research Officer
(Chemistry, Mathematics & Statistics)