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International Human Frontier Science Research Grants

Opportunity NameResearch Grants
AgencyInternational Human Frontier Science Program Organization (HFSPO)
ValueTeam of 2 — $300,000 USD
Team of 3 — $400,000 USD
Team of 4 — $500,000 USD
Indirect CostsEligible at 10%
Duration3 years

Letter of Intent (LOI)

LOI application due to FSc RO at for full review03-16-2023
Compulsory initiation of a LOI due at agency (by obtaining a 7-digit LOI ID)03-21-2023
LOI application and fully signed ORS checklist due to FSc RO at for mandatory review03-23-2023
Final LOI application and fully signed ORS checklist due at ORS for mandatory review03-28-2023
LOI application due at agency 03-30-2023

Full application (by invitation only)

Application due to FSc RO at for full reviewTBD
Application and fully signed ORS checklist due to FSc RO at for mandatory reviewTBD
Final application and fully signed ORS checklist due at ORS for mandatory reviewTBD
Application due at agency TBD (Mid-September 2023)
  • To strengthen open scientific inquiry by initiating international collaborative, interdisciplinary and cutting-edge basic research in the life sciences. 
  • To promote, through international cooperation, basic research focused on the elucidation of the sophisticated and complex mechanisms of living organisms, for the benefit of all humankind.

HFSPO attaches highest importance to novelty, scientific merit, internationality, and interdisciplinarity. Research topics may include biological functions at all levels of analysis: for example, studies on genes and individual molecules, intracellular networks, intercellular associations in tissues and organs, and networks underlying the complex functions of entire organisms including cognitive functions, as well as populations or ecosystems. 

The participation of scientists from disciplines outside the traditional life sciences such as physics, chemistry, computational biology, engineering, mathematics, nanoscience, physics, or psychology is highly encouraged.

Two types of grants are available: 

Research Grants – Early Career (RG – Early Career): to encourage outstanding scientists in the initial period of their independent careers, to formulate innovative and promising research projects. Typically, “Early Career” team members will have completed one or two periods of postdoctoral training and recently been appointed to independent staff positions that allow them to initiate and direct their own independent lines of research.

Research Grants – Program (RG – Program): to allow teams of independent researchers to develop new lines of research through a new collaboration. Priority will be given to novel research projects with the potential to extend the present frontier of the life sciences and teams including members from outside the life sciences. Applicants for RG-Program are encouraged to include independent investigators early in their careers as members of their team.

  • The Principal Applicant of a Research Grant must have a laboratory in a member country (with the exception of HFSP Career Development Awardees). The other team members and their laboratories may be situated anywhere in the world.
  • All team members are expected to direct a research group (however small) and must have a doctoral degree (PhD, MD or equivalent). They must be in a position to initiate and direct their own independent lines of research. The HFSP award is not intended to create scientific independence, this is a decision of the research institute prior to the application.
  • All team members must be able to determine the course of the HFSP-funded project and have freedom to administer the grant, if awarded.
  • The research teams must be international (preferably intercontinental). Normally, there will be only one team member with a laboratory in each country, teams with two members at the same institution are not eligible.
  • Team members should not have collaborated before, they will normally not have published original research together, and the project must be significantly different from their ongoing research.

How to Apply

York University researchers are reminded that all applications for external research funding, including Letters of Intent, must be reviewed and approved by the Office of Research Services before they are submitted to the granting agency.  For internal approval, the application must be accompanied by a completed ORS Checklist, which requires the Dean’s signature.  Please send the complete application, with the finalized budget and a completed ORS checklist to, five days prior to agency deadline.

ORS is accepting electronic applications – the process is outlined here.

For specific questions, please contact FSc Research Services at