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Home » Research » Funding Opportunities » OICR Cancer Therapeutics Innovation Pipeline: Early Validation Projects

OICR Cancer Therapeutics Innovation Pipeline: Early Validation Projects

Opportunity NameEarly Validation Projects
AgencyOntario Institute for Cancer Research
ValueUp to $150,000/year
Indirect CostsEligible at 30%
DurationUp to 2 years

Note: The deadline for submission of the Notice of Intent (NOI) is the same as the deadline for Letter of Intent (LOI) submission, however, applicants are encouraged to submit their NOI as early as possible to assist with planning and to ensure sufficient time to complete the LOI by the deadline. 

Information session06-30-2022, 2:00 - 3:00PM
Letter of Intent (LOI) due to FSc RO at for full review06-28-2022
LOI and fully signed ORS checklist due to FSc RO at for mandatory review07-06-2022
Final LOI and fully signed ORS checklist due at ORS for mandatory review07-11-2022, by 9:00AM
LOI due at agency 07-13-2022, by 5:00PM
Notice of Intent (NOI) submission07-13-2022, by 5:00PM
Application due to FSc RO at for full review09-21-2022
Application and fully signed ORS checklist due to FSc RO at for mandatory review09-28-2022
Final application and fully signed ORS checklist due at ORS for mandatory review10-03-2022, by 9:00AM
Application due at agency (by invitation only)10-05-2022, by 5:00PM

Deliver robust translational evidence that a Target-of-Interest (TOI) is associated with a specific cancer type(s) based on data from knowledge bases and from studies demonstrating that perturbation of the TOI in relevant cell-based models produces anti-cancer effects sufficient to trigger a drug discovery campaign. 

The overall objectives of this program are to:

  • Create a pipeline of validated cancer targets and first-in-class or best-in-class, novel, selective lead molecules (small molecules or biologics) that will attract partnerships and/or investment for further preclinical and clinical development; and
  • Support projects that aim to provide increasing evidence of target validation and disease association using data from knowledge bases, functional assays, and drug screening in relevant in vitro and in vivo models of the cancer type of interest. 

  • OICR invites applications from investigators at Ontario academic centres, hospital research institutes or other government research institutions. CTIP funding is only tenable in Ontario.
    • For profit entities are not eligible to receive CTIP funding.
  • Investigators are eligible to participate on and submit multiple CTIP submissions via this RFA.

How to Apply

York University researchers are reminded that all applications for external research funding, including Letters of Intent, must be reviewed and approved by the Office of Research Services before they are submitted to the granting agency.  For internal approval, the application must be accompanied by a completed ORS Checklist, which requires the Dean’s signature.  Please send the complete application, with the finalized budget and a completed ORS checklist to, five days prior to agency deadline.

ORS is accepting electronic applications – the process is outlined here.

Information Session

An information session will be held on June 30, 2022 from 2:00 - 3:00PM.

For specific questions, please contact your FSc Research Officer

Stefanie Bernaudo
Research Officer
(Biology, Physics & Astronomy, Science, Technology & Society)

Phoebe Tsz-Wai Chan
Research Officer
(Chemistry, Mathematics & Statistics)