Details
| Opportunity Name | Systematic Review: Occupational exposure to diesel engine exhaust (DEE) and lung and bladder cancers |
| Agency | Ontario Workplace Safety and Insurance Board (WSIB) |
| Value | $200,000 |
| Indirect Costs | Ineligible |
| Duration | Up to 18 months |
Deadlines
| Application due to FSc RO at sciapps@yorku.ca for full review | 01-15-2024 |
| Application and fully signed ORS checklist due to FSc RO at sciapps@yorku.ca for mandatory review | 01-22-2024 |
| Final application and fully signed ORS checklist due at ORS for mandatory review | 01-25-2024, by 9:00AM |
| Application due at agency | 01-29-2024, by 5:00PM |
Objective
To enhance workplace injury and illness insurance system outcomes by supporting innovative proposals that help advance WSIB’s strategic mandate.
The specific aims are to:
- evaluate the evidence on occupational exposure to diesel engine exhaust (DEE) and the development of primary site cancers of the lung (ICD-9 162, ICD-10 C33-34) and bladder (ICD-9 188, ICD-10 C67);
- examine exposure-response relationships by detailed exposure characteristics;
- identify industries and occupations with high risk of lung or bladder cancer development; and
- evaluate the potential for synergistic relationships between DEE and other risk factors for lung or bladder cancer.
The review must address:
- occupational exposure to DEE and development of primary-site cancers of the lung and bladder among exposed workers
- the identification and assessment of:
- industries and occupations with high risk of lung or bladder cancer with occupational exposure to DEE (e.g., mining, transportation)
- the shape and distribution of the relationship between DEE exposure and lung/bladder cancer development; the effect of highest levels compared with lowest levels of DEE exposure on lung/bladder cancer development; any exposure-response trends of increasing risk with increasing exposure using exposure surrogates such as average exposure, duration, cumulative exposure and whether there is a minimum cumulative exposure associated with increased risk
- minimal interval (latency) between the first exposure and the development of lung or bladder cancer
- any interdependent causes or synergistic relationships with other risk factors (e.g., exposure to other carcinogens)
Eligibility
The research team will require a minimum of three (3) team members including:
- At least one member with a doctorate in epidemiology
- At least one member who has formal training or industry hygiene (Masters Level or PhD)
- At least one member of the team must have demonstrated experience conducting systematic reviews including meta-analyses related to disease etiology
In addition, the ideal research team may also include:
- at least one member who is a MD with a specialization in occupational medicine or oncology.
Expert researchers affiliated with an eligible applicant organization:
- Publicly funded universities or colleges
- Public hospitals with a specialized research area
- Not-for-profit or registered charitable organizations with the capability and capacity to conduct research
- Canadian non-governmental organizations with the capability and capacity to conduct research
- Other organizations that have the capability and capacity to conduct research and are not privately owned and operated may also be eligible for a WSIB grant.
Private organizations are not eligible to apply for a WSIB research grant as a project or secondary lead. Private organizations may be identified as a partner or collaborator of an eligible applicant organization.
How to Apply
York University researchers are reminded that all applications for external research funding, including Letters of Intent, must be reviewed and approved by the Office of Research Services before they are submitted to the granting agency. For internal approval, the application must be accompanied by a completed ORS Checklist, which requires the Dean’s signature. Please send the complete application, with the finalized budget and a completed ORS checklist to sciapps@yorku.ca, five days prior to agency deadline.
ORS is accepting electronic applications – the process is outlined here.